CPT 88261 Pathology/Laboratory

How Much Does Chromosome Analysis for Genetic Defects, Count 5 Cells Cost?

Also known as: Chromosome analysis for genetic defects, count 5 cells (CPT 88261)

Chromosome Analysis for Genetic Defects, Count 5 Cells (CPT 88261) costs $264 at Medicare rates.

Medicare (Facility)
$264
CMS PFS 2026 national rate

Procedures Commonly Done Together

These procedures are frequently performed alongside Chromosome analysis for genetic defects, count 5 cells

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How to Reduce Your Cost for Chromosome analysis for genetic defects, count 5 cells

Practical tips that can save you hundreds or thousands of dollars

  • 1
    Ask about cash-pay discounts

    Many hospitals and clinics offer 20-40% discounts for self-pay patients. Always ask before scheduling.

  • 2
    Compare facility vs. office setting costs

    Some procedures cost significantly less in an office setting than a hospital. Ask your provider about options.

  • 3
    Shop around — costs vary significantly

    Costs can vary 2-3x between providers in the same city. Get quotes from multiple facilities.

Frequently Asked Questions

How much does Chromosome analysis for genetic defects, count 5 cells cost?

The Medicare facility rate for Chromosome analysis for genetic defects, count 5 cells is $264. Commercial insurance rates typically range from 150% to 250% of Medicare (varies by plan).

How much does Chromosome analysis for genetic defects, count 5 cells cost without insurance?

Without insurance, the cost of Chromosome analysis for genetic defects, count 5 cells can range from 150% of Medicare to 500% of Medicare depending on the facility. Many hospitals and clinics offer self-pay discounts of 20-40% off their chargemaster price. Always ask about cash pricing before your visit.

Does insurance cover Chromosome analysis for genetic defects, count 5 cells?

Most commercial health insurance plans and Medicare cover Chromosome analysis for genetic defects, count 5 cells when ordered by a physician for a medically necessary reason. Your out-of-pocket cost depends on your plan's deductible, copay/coinsurance structure, and whether you use an in-network provider. Check with your insurance company before scheduling to confirm coverage and get a cost estimate.

Why does the cost vary so much by location?

Medicare adjusts payments using Geographic Practice Cost Indices (GPCIs) that reflect local differences in physician work costs, practice expenses, and malpractice insurance. Manhattan, San Francisco, and other high-cost areas pay significantly more than rural regions. Commercial insurers follow similar geographic patterns.

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