Is there a generic version of Refresh Plus?

Refresh Plus is a brand name medication. Generic alternatives may be available — ask your pharmacist or search our drug database for equivalent generics, which typically cost 80-85% less.

Brand Name NDC 00023040370

Refresh Plus 0.5% Eye Drops

NADAC pharmacy acquisition cost from CMS

NADAC Per Unit

$0.2595

Pharmacy acquisition cost

Est. 30-Day Supply

At NADAC cost (1/day)

Est. 90-Day Supply

$23

At NADAC cost (1/day)

Est. Retail Price / Unit

$0.3504

~35% pharmacy markup

Est. Retail 30-Day

$11

Without insurance

Est. Annual Cost

$128

Retail, 1 unit/day

Generic Alternatives to Refresh Plus

These generic drugs have similar dosage forms and may be alternatives. Ask your pharmacist or doctor about switching.

Lubricant 0.5% Eye Drops Generic

$0.1875

28% less

Tetracaine 0.5% Eye Drops Generic

$0.5559

Timolol Maleate 0.5% Eye Drops Generic

$1.07

Proparacaine 0.5% Eye Drops Generic

$1.61

Moxifloxacin 0.5% Eye Drops Generic

$1.77

See full comparison →

Understanding Drug Pricing

NADAC (shown above) — What the pharmacy pays the wholesaler for this drug. This is the most transparent baseline cost, published weekly by CMS.

Retail Price — Pharmacies add a dispensing fee ($2-$15) and markup (20-50%). This is what you pay without insurance or discount cards.

Insurance Copay — With insurance, you typically pay a flat copay ($5-$15 generic, $25-$50 brand) regardless of the NADAC cost.

Frequently Asked Questions

How much does Refresh Plus cost?

The pharmacy acquisition cost (NADAC) for Refresh Plus 0.5% Eye Drops is $0.2595 per unit. A 30-day supply at 1 unit per day costs approximately $8.

How much does Refresh Plus cost without insurance?

Without insurance, expect to pay approximately $11 for a 30-day supply. Pharmacy discount programs (GoodRx, RxSaver, Cost Plus Drugs) and manufacturer coupons can reduce this significantly. Ask your doctor if a generic alternative is available — generics typically cost 80-85% less.

Is Refresh Plus available as a generic?

Refresh Plus is a brand name medication. Generic alternatives may be available. Ask your pharmacist about equivalent generics which can save 80-85%.