Brand Name NDC 00169431430

Rybelsus 14 MG TABLET

NADAC pharmacy acquisition cost from CMS

NADAC Per Unit
$33.17
Pharmacy acquisition cost
Est. 30-Day Supply
$995
At NADAC cost (1/day)
Est. 90-Day Supply
$2,985
At NADAC cost (1/day)
Est. Retail Price / Unit
$44.78
~35% pharmacy markup
Est. Retail 30-Day
$1,343
Without insurance
Est. Annual Cost
$16,343
Retail, 1 unit/day

About Rybelsus

Rybelsus is the only oral (tablet) GLP-1 medication, taken daily for type 2 diabetes. It contains semaglutide, the same active ingredient as Ozempic, but in pill form instead of injection.

Understanding Drug Pricing

1
NADAC (shown above) — What the pharmacy pays the wholesaler for this drug. This is the most transparent baseline cost, published weekly by CMS.
2
Retail Price — Pharmacies add a dispensing fee ($2-$15) and markup (20-50%). This is what you pay without insurance or discount cards.
3
Insurance Copay — With insurance, you typically pay a flat copay ($5-$15 generic, $25-$50 brand) regardless of the NADAC cost.

Frequently Asked Questions

How much does Rybelsus cost?

The pharmacy acquisition cost (NADAC) for Rybelsus 14 MG TABLET is $33.17 per unit. A 30-day supply at 1 unit per day costs approximately $995.

How much does Rybelsus cost without insurance?

Without insurance, expect to pay approximately $1,343 for a 30-day supply. Pharmacy discount programs (GoodRx, RxSaver, Cost Plus Drugs) and manufacturer coupons can reduce this significantly. Ask your doctor if a generic alternative is available — generics typically cost 80-85% less.

Is Rybelsus available as a generic?

Rybelsus is a brand name medication. Generic alternatives may be available. Ask your pharmacist about equivalent generics which can save 80-85%.

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