Generic NDC 00378464316
Estradiol 0.0375 MG PATCH
NADAC pharmacy acquisition cost from CMS
NADAC Per Unit
$8.39
Pharmacy acquisition cost
Est. 30-Day Supply
$252
At NADAC cost (1/day)
Est. 90-Day Supply
$755
At NADAC cost (1/day)
Est. Retail Price / Unit
$11.32
~35% pharmacy markup
Est. Retail 30-Day
$340
Without insurance
Est. Annual Cost
$4,133
Retail, 1 unit/day
Understanding Drug Pricing
1
NADAC (shown above) — What the pharmacy pays the wholesaler for this drug.
This is the most transparent baseline cost, published weekly by CMS.
2
Retail Price — Pharmacies add a dispensing fee ($2-$15) and markup (20-50%).
This is what you pay without insurance or discount cards.
3
Insurance Copay — With insurance, you typically pay a flat copay
($5-$15 generic, $25-$50 brand) regardless of the NADAC cost.
Frequently Asked Questions
How much does Estradiol cost?
The pharmacy acquisition cost (NADAC) for Estradiol 0.0375 MG PATCH is $8.39 per unit. A 30-day supply at 1 unit per day costs approximately $252.
How much does Estradiol cost without insurance?
Without insurance, expect to pay approximately $340 for a 30-day supply. Pharmacy discount programs (GoodRx, RxSaver, Cost Plus Drugs) and manufacturer coupons can reduce this significantly.
Is Estradiol available as a generic?
Yes, Estradiol is a generic medication and is typically the most affordable option.