Generic NDC 00409263450
Hydromorphone 500 Mg/50 ML Vial
NADAC pharmacy acquisition cost from CMS
NADAC Per Unit
$2.52
Pharmacy acquisition cost
Est. 30-Day Supply
$76
At NADAC cost (1/day)
Est. 90-Day Supply
$227
At NADAC cost (1/day)
Est. Retail Price / Unit
$3.41
~35% pharmacy markup
Est. Retail 30-Day
$102
Without insurance
Est. Annual Cost
$1,244
Retail, 1 unit/day
Understanding Drug Pricing
1
NADAC (shown above) — What the pharmacy pays the wholesaler for this drug.
This is the most transparent baseline cost, published weekly by CMS.
2
Retail Price — Pharmacies add a dispensing fee ($2-$15) and markup (20-50%).
This is what you pay without insurance or discount cards.
3
Insurance Copay — With insurance, you typically pay a flat copay
($5-$15 generic, $25-$50 brand) regardless of the NADAC cost.
Frequently Asked Questions
How much does Hydromorphone cost?
The pharmacy acquisition cost (NADAC) for Hydromorphone 500 Mg/50 ML Vial is $2.52 per unit. A 30-day supply at 1 unit per day costs approximately $76.
How much does Hydromorphone cost without insurance?
Without insurance, expect to pay approximately $102 for a 30-day supply. Pharmacy discount programs (GoodRx, RxSaver, Cost Plus Drugs) and manufacturer coupons can reduce this significantly.
Is Hydromorphone available as a generic?
Yes, Hydromorphone is a generic medication and is typically the most affordable option.