Generic NDC 00536101506
Acetaminophen-diphenhydramine 500 Mg-25 MG TABLET
NADAC pharmacy acquisition cost from CMS
NADAC Per Unit
$0.0432
Pharmacy acquisition cost
Est. 30-Day Supply
$1
At NADAC cost (1/day)
Est. 90-Day Supply
$4
At NADAC cost (1/day)
Est. Retail Price / Unit
$0.0583
~35% pharmacy markup
Est. Retail 30-Day
$2
Without insurance
Est. Annual Cost
$21
Retail, 1 unit/day
Understanding Drug Pricing
1
NADAC (shown above) — What the pharmacy pays the wholesaler for this drug.
This is the most transparent baseline cost, published weekly by CMS.
2
Retail Price — Pharmacies add a dispensing fee ($2-$15) and markup (20-50%).
This is what you pay without insurance or discount cards.
3
Insurance Copay — With insurance, you typically pay a flat copay
($5-$15 generic, $25-$50 brand) regardless of the NADAC cost.
Frequently Asked Questions
How much does Acetaminophen-diphenhydramine cost?
The pharmacy acquisition cost (NADAC) for Acetaminophen-diphenhydramine 500 Mg-25 MG TABLET is $0.0432 per unit. A 30-day supply at 1 unit per day costs approximately $1.
How much does Acetaminophen-diphenhydramine cost without insurance?
Without insurance, expect to pay approximately $2 for a 30-day supply. Pharmacy discount programs (GoodRx, RxSaver, Cost Plus Drugs) and manufacturer coupons can reduce this significantly.
Is Acetaminophen-diphenhydramine available as a generic?
Yes, Acetaminophen-diphenhydramine is a generic medication and is typically the most affordable option.