CPT 81521 Pathology/Laboratory

Gene analysis of breast tumor tissue, profiling of 70 content genes and 465 Cost

Body System: General

Medicare Facility Rate
$3,873
CMS PFS CY2026
Medicare Non-Facility Rate
$3,873
Office/clinic setting

Frequently Asked Questions

How much does Gene analysis of breast tumor tissue, profiling of 70 content genes and 465 cost?

The Medicare facility rate is $3,873. Commercial insurance typically pays 150-250% of Medicare rates (varies).

How much does Gene analysis of breast tumor tissue, profiling of 70 content genes and 465 cost without insurance?

Without insurance, you may pay the hospital's chargemaster rate, which is often 300-500% of Medicare. Ask about cash-pay discounts — many facilities offer 20-40% off for self-pay patients. The Medicare baseline for this procedure is $3,873.

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